Medieval inguinal plague was first recorded in the 14th century and was the beginning of a 500-year wave of deadly diseases called the Second Plague Pandemic. The Black Death killed millions and was considered one of the greatest disasters of infectious diseases in human history. Despite years of research, the geographical and chronological origin of the disease remained a mystery. Our study finally raises one of the biggest and most exciting questions in history and determines when and where the only most notorious and notorious murderer of humans began. Dr. Philip Slavin, University of Stirling However, researchers say they believe the Black Death first originated in northern Kyrgyzstan in the late 1330s. The team, from the University of Stirling in Scotland and the Max Planck Institute in Germany and the University of Tubingen, analyzed ancient DNA (aDNA) obtained from skeletal teeth found in cemeteries near Lake Issyk Kul in the Tian Shan region of Kyrgyzstan. They were pulled to these sites after spotting a huge increase in the number of tombs there in 1338 and 1339, according to Stirling University historian Dr Philip Slavin, who assisted in the discovery. The team found that the cemeteries in Kara-Djigach and Burana had already been excavated in the late 1880s, with about 30 skeletons taken from the graves, but were able to locate them and analyze the DNA obtained. from the teeth of seven people. The sequence, which determines the structure of DNA, showed three people carrying Yersinia pestis, a bacterium linked to the onset of the Black Death epidemic before it reached Europe. “Our study concludes with one of the biggest and most exciting questions in history and determines when and where the most notorious and notorious killer of humans began,” said Dr. Slavin. Part of his job was to study the historical calendars of the original excavations in order to match the individual skeletons with their tombstones, carefully translating the inscriptions, which were written in the Syrian language. Dr. Maria Spyrou, from the University of Tubingen, and the first author of the study, said: “Despite the risk of environmental pollution and no guarantee that the bacteria could be preserved, we were able to identify the DNA sequence obtained from seven people who were discovered by two of these cemeteries. “The most exciting thing is that we found a DNA of the plague bacterium in three people.” Johannes Krause, a professor at the Max Planck Institute for Evolutionary Anthropology in Leipzig, added: “Just like Covid, the Black Death was an emerging disease and the beginning of a huge pandemic that lasted for about 500 years. “It’s very important to really understand under what circumstances it came about.” The origin of the Black Death has been debated by historians for centuries and is believed by medieval chroniclers to have appeared in Europe, the Middle East and North Africa 675 years ago. The research study, The Source of the Black Death in Central Eurasia in the 14th Century, was published in the journal Nature.